07  /  16  /  2021

Targeting protein phosphatase PP2A for cancer therapy: development of allosteric pharmaceutical agents

10  /  07  /  2020

The SRG rat, a Sprague-Dawley Rag2/Il2rg double-knockout validated for human tumor oncology studies

04  /  20  /  2020

Selective PP2A Enhancement through Biased Heterotrimer Stabilization

12  /  10  /  2019

Protein phosphatase 2A activation as a therapeutic strategy for managing MYC-driven cancers

09  /  27  /  2019

Protein phosphatase 2A controls ongoing DNA replication by binding to and regulating cell division cycle 45 (CDC45)

09  /  20  /  2019

Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors

05  /  29  /  2019

The Highly Recurrent PP2A Aα-Subunit Mutation P179R Alters Protein Structure and Impairs PP2A Enzyme Function to Promote Endometrial Tumorigenesis

07  /  17  /  2018

PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells

04  /  01  /  2018

Small-Molecule Activators of Protein Phosphatase 2A for the Treatment of Castration-Resistant Prostate Cancer

10  /  08  /  2017

Therapeutic targeting of PP2A

05  /  15  /  2017

Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth

10  /  28  /  2015

All roads lead to PP2A: Exploiting the therapeutic potential of this phosphatase

12  /  16  /  2014

Repurposing of bisphosphonates for the prevention and therapy of non-small cell lung and breast cancer

11  /  11  /  2014

Bisphosphonates inactivate human EGFRs to exert anti-tumor actions

01  /  07  /  2014

microRNA-181a has a critical role in ovarian cancer progression through the regulation of the epithelial–mesenchymal transition

01  /  23  /  2013

KLF6-SV1 drives breast cancer metastasis and is associated with poor survival

06  /  01  /  2012

Targeting the FOXO1/KLF6 axis regulates EGFR signaling and treatment response

07  /  01  /  2005

Targeted inhibition of the KLF6 splice variant KLF6SV1 suppresses prostate cancer growth and spread

02  /  01  /  2005

A germline DNA polymorphism enhances alternative splicing of the KLF6 tumor suppressor gene and is associated with increased prostate cancer risk

12  /  21  /  2001

KLF6, a candidate tumor suppressor gene in prostate cancer

04  /  01  /  1995

The apolipoprotein(a) gene is regulated by sex hormones and acute phase inducers in YAC transgenic mice
Read all published papers from the Narla Lab here.